Can the Modbus ASCII driver connect a TI545 to Wonderware.

If the TI is configured to talk Modbus ASCII it would. Make sure this is true as there are other drivers that would communicate to this PLC type with other protocols.

Click for videos and appnotes on how to connect TOP Server to Wonderware Products.

The TOP Server Simatic/TI Suite is likely a better fit for connectivity to a TI 545 PLC from Wonderware.